Abstract：Estuarine wetlands play an important role in global terrestrial ecosystem carbon cycles. In order to reveal the effects of saltwater intrusion on the soil carbon mineralization potential in estuarine wetlands， this study used a fine-scale salinity gradient to determine the impact of saltwater concentration on soil carbon mineralization potential （represented by CO2 production） and associated soil properties from the Min River Estuary freshwater wetland， using indoor mud anaerobic incubation with gas chromatography methods for three consecutive weeks. The results showed： ①Under different salinity treatments， soil pH values were lower than that under the control （0）， ammonia nitrogen （NH4+-N） content were higher than that under the control， and increased with increasing salinity. Soluble organic carbon （DOC） contents were higher in 25‰ and 30‰ salinity treatments than that in the control. The contents of SO42- in 20‰， 25‰ and 30‰ treatments were higher than that in the control. ②With the change of incubated time， the potential of CO2 production in the first week of anaerobic incubation was significantly higher than that in the second and third weeks （p＜0.05）， and the potential of CO2 production in different salinity treatments was significantly different， presenting the promoting effect of lower salinity （0.5‰~10‰） and inhibiting effect of higher salinity （15‰~30‰）， indicated salinities of 10‰~15‰ represented an important turning point for soil carbon mineralization in wetlands. ③There was a significant positive correlation between CO2 production potential and soil pH under different salinity treatments， and a significant negative correlation between CO2 production potential and soil conductivity（EC）， NH4+-N， Cl-， SO42- and DOC. Overall， salinity is an important factor affecting soil carbon mineralization in estuarine wetlands. Carbon mineralization may be reduced in higher-level saltwater intrusion， meanwhile， lower-level saltwater intrusion may leave estuarine wetlands vulnerable to submergence due to accelerated soil organic carbon loss.