Abstract：The chloromethylated polystyrene resin（CMPS）was used as a precursor to synthesize ultra-high cross-linked resin （J-2） by post-cross-linking reaction， and then modified by thiourea amino to produce thiourea amino-modified ultra-high cross-linked polystyrene resin （TU-PS）. The structure of the modified resin was characterized by the BET and FTIR， and the adsorption performance of the TU-PS modified resin on Cr（VI） was investigated under pH， temperature， contact time and other factors. The results demonstrated that： ①the optimal adsorption condition of Cr（VI） by the TU-Ps was as followed： Initial concentration of Cr（VI） was 500 mg L-1， initial pH value was 2， modified resin dosage was 2.5 g·L-1， adsorption temperature was 45 ℃， adsorption time was 6 h. ②Under the optimal condition， the maximum equilibrium adsorption capacity of Cr（VI） on the TU-PS was 140.00 mg·g-1， and the removal rate is 70.18%. ③The adsorption process was in accordance with the Langmuir isothermal adsorption model and quasi-secondary kinetic model， and the adsorption process was dominated by single-molecule layer chemisorption. ④The adsorption of Cr（VI） by the TU-PS was resulted by the electrostatic adsorption and chemisorption.